Although this manual is primarily designed for creating a common language for clinical practice, it is also often used in research settings to define the conditions to be studied. While acknowledging concerns about issues such as diagnostic inflation and financial conflicts of interest, DSM-5 is now “set in stone" and will be published in May 2013. The two international psychiatric classification systems (the Diagnostic and Statistical Manual of Mental Disorders and the International Classification of Diseases ) remain useful for making clinical diagnoses, but each time these classification systems are revised, the new definitions inevitably subtly change the nature of how the conditions are construed. The biology of autism cannot yet be used diagnostically, and so-like most psychiatric conditions-autism is defined by behavior. Quantitative Checklist for Autism in Toddlers SRS, US National Institute of Mental Health PDD, International Classification of Diseases NIMH, The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.Īutism Spectrum Screening Questionnaire BAP,ĭiagnostic and Statistical Manual of Mental Disorders ICD, Simon Baron-Cohen is supported by the Wellcome Trust ( ) and the Medical Research Council, UK. Bhismadev Chakrabarti is supported by the Medical Research Council, UK ( ). Lombardo is supported by the British Academy ( ) and Jesus College, Cambridge ( ). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: Meng-Chuan Lai is supported by the Waterloo Foundation ( ), Wolfson College, Cambridge ( ), and the European Autism Interventions – A Multicentre Study for Developing New Medications (EU-AIMS, the research of EU-AIMS receives support from the Innovative Medicines Initiative Joint Undertaking under grant agreement n° 115300, resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007–2013), from the EFPIA companies in kind contribution and from Autism Speaks). PLoS Biol 11(4):Īcademic Editor: Eric Nestler, Mount Sinai School of Medicine, United States of AmericaĬopyright: © 2013 Lai et al. Citation: Lai M-C, Lombardo MV, Chakrabarti B, Baron-Cohen S (2013) Subgrouping the Autism “Spectrum": Reflections on DSM-5.
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